Explore the latest peer-reviewed research with AI-generated summaries, key findings, and insights for easy understanding. All content is legally sourced from academic metadata with links to original papers.
In vitro, B.1.617.2 is sixfold less sensitive to serum neutralizing antibodies from recovered individuals, and eightfold less sensitive to vaccine-elicited antibodies, compared with wild-type Wuhan-1...
Obesity is a complex multifactorial disease that accumulated excess body fat leads to negative effects on health. This review summarizes the global trends in obesity with a special focus on the pathog...
Providing healthcare services that respect and meet patients' and caregivers' needs are essential in promoting positive care outcomes and perceptions of quality of care, thereby fulfilling a significa...
This research explores Immune checkpoint inhibitors in melanoma, contributing new insights to the field of Medicine & Biology.
Late-onset Alzheimer's disease is a prevalent age-related polygenic disease that accounts for 50-70% of dementia cases. This study highlights microglia, immune cells and protein catabolism as relevant...
Background While it is now apparent clinical sequelae (long COVID) may persist after acute COVID-19, their nature, frequency and aetiology are poorly characterised. There is an urgent need for prospec...
All laws are built on the premise that individuals have a will and act according to their will. Hence, the academic field of "neurolaw" is born, and the court of criminal trials is a scene of natural...
Breakthroughs in molecular medicine have positioned the amyloid-β (Aβ) pathway at the center of Alzheimer's disease (AD) pathophysiology. We discuss the evidence highlighting a differentiated interact...
This research explores Application of glutathione depletion in cancer therapy: Enha..., contributing new insights to the field of Medicine & Biology.
The ESC Guidelines represent the views of the ESC and were produced after careful consideration of the scientific and medical knowledge and the evidence available at the time of their publication. Nor...
BACKGROUND: Finerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, has favorable effects on cardiorenal outcomes in patients with predominantly stage 3 or 4 chronic kidney disease...
BACKGROUND: The COVID-19 pandemic has posed an unprecedented threat to global mental health. Physical exercise, access to entertainment, positive familial relationships, and social support were associ...
BACKGROUND: Sodium-glucose cotransporter 2 inhibitors reduce the risk of hospitalization for heart failure in patients with heart failure and a reduced ejection fraction, but their effects in patients...
The COVID-19 pandemic has revealed critical knowledge gaps in our understanding of and a need to update the traditional view of transmission pathways for respiratory viruses. In this Review, we discus...
Breast cancer (BC) is the most frequently diagnosed cancer in women worldwide with more than 2 million new cases in 2020. The eighth edition of TNM classification outlines a new staging system for BC...
This research explores mRNA vaccines for infectious diseases: principles, delivery..., contributing new insights to the field of Medicine & Biology.
Photodynamic therapy (PDT) is a minimally invasive therapeutic modality that has gained great attention in the past years as a new therapy for cancer treatment. Moreover, the future path on the resear...
BACKGROUND: Preapproval trials showed that messenger RNA (mRNA)-based vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had a good safety profile, yet these trials were sub...
Brain and other central nervous system (CNS) tumors are among the most fatal cancers and account for substantial morbidity and mortality in the United States. In addition, important survival dispariti...
This research explores Cardiovascular, mortality, and kidney outcomes with GLP-1 re..., contributing new insights to the field of Medicine & Biology.