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Breast Cancer—Epidemiology, Risk Factors, Classification, Prognostic Markers, and Current Treatment Strategies—An Updated Review

📅 August 25, 2021 👤 Sergiusz Łukasiewicz, Marcin Czeczelewski, Alicja Forma et al. 📖 Cancers 📊 1,828 citations

🤖 Plain-English Summary

Breast cancer (BC) is the most frequently diagnosed cancer in women worldwide with more than 2 million new cases in 2020. The eighth edition of TNM classification outlines a new staging system for BC that, in addition to anatomical features, acknowledges biological factors.

🔑 Key Findings

  • Its incidence and death rates have increased over the last three decades due to the change in risk factor profiles, better cancer registration, and cancer detection.
  • The number of risk factors of BC is significant and includes both the modifiable factors and non-modifiable factors.
  • Currently, about 80% of patients with BC are individuals aged >50.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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📋 Article Details

Category 🧬 Medicine & Biology
Published Aug 25, 2021
Journal Cancers
Authors Sergiusz Łukasiewicz, Marcin Czeczelewski, Alicja Forma, Jacek Baj, Robert Sitarz
DOI 10.3390/cancers13174287
Citations 1,828
Source OpenAlex

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