Research Article Hub

Explore the latest peer-reviewed research with AI-generated summaries, key findings, and insights for easy understanding. All content is legally sourced from academic metadata with links to original papers.

2,222Articles
5Disciplines
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🧬 Medicine & Biology OpenAlex

Large-scale integration of the plasma proteome with genetics and disease

📅 Dec 2021 👤 Egil Ferkingstad, Patrick Sulem, Bjarni A. Atlason et al. 📊 1,652 citations

This research explores Large-scale integration of the plasma proteome with genetics..., contributing new insights to the field of Medicine & Biology.

🧬 Medicine & Biology OpenAlex

The European Union One Health 2020 Zoonoses Report

📅 Dec 2021 👤 European Food Safety Authority 📊 1,570 citations

This research explores European Union One Health 2020 Zoonoses Report, contributing new insights to the field of Medicine & Biology.

🧬 Medicine & Biology OpenAlex

Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic

📅 Dec 2021 👤 Salim S Abdool Karim, Quarraisha Abdool Karim 📊 1,317 citations

This research explores Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pa..., contributing new insights to the field of Medicine & Biology.

🧬 Medicine & Biology OpenAlex

Nanoparticles for Cancer Therapy: Current Progress and Challenges

📅 Dec 2021 👤 Shreelaxmi Gavas, Sameer Quazi, Tomasz M. Karpiński 📊 983 citations

Cancer is one of the leading causes of death and morbidity with a complex pathophysiology. This review discusses numerous types of nanoparticles, targeting mechanisms, and approved nanotherapeutics fo...

🧬 Medicine & Biology PubMed

Maximizing insights from monogenic immune disorders.

📅 Dec 2021 👤 Barmada Anis, Ramaswamy Anjali, Lucas Carrie L

Monogenic immune disorders provide unprecedented insights into the consequences of disrupting single genes in humans, thereby informing our understanding of fundamental immune function and disease. At...

🧬 Medicine & Biology PubMed

Tumor immunology in the age of single-cell genomics.

📅 Dec 2021 👤 Zhao Lingyu, Ren Lili, Gao Shuangshu et al.

Immunotherapies that were developed based on our understandings of tumor immunology have revolutionized cancer treatment. Future studies on tumor immunology in the age of single-cell genomics, therefo...

🧬 Medicine & Biology PubMed

2021 SNMMI Highlights Lecture: Neuroscience.

📅 Dec 2021 👤 Price Julie

The Journal of Nuclear Medicine

🧬 Medicine & Biology OpenAlex

The JAK/STAT signaling pathway: from bench to clinic

📅 Nov 2021 👤 Xiaoyi Hu, Jing Li, Maorong Fu et al. 📊 2,445 citations

The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway was discovered more than a quarter-century ago. In this review, we discuss the current knowledge about th...

🧬 Medicine & Biology OpenAlex

Cytochrome P450 Enzymes and Drug Metabolism in Humans

📅 Nov 2021 👤 Mingzhe Zhao, Jingsong Ma, Mo Li et al. 📊 953 citations

Human cytochrome P450 (CYP) enzymes, as membrane-bound hemoproteins, play important roles in the detoxification of drugs, cellular metabolism, and homeostasis. In this review, we summarize and highlig...

🧬 Medicine & Biology OpenAlex

Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients W...

📅 Nov 2021 👤 Jedd D. Wolchok, Vanna Chiarion-Sileni, Rene Gonzalez et al. 📊 1,097 citations

PURPOSE: In the phase III CheckMate 067 trial, durable clinical benefit was demonstrated previously with nivolumab plus ipilimumab and nivolumab alone versus ipilimumab. Since the 5-year analysis, no...

🧬 Medicine & Biology OpenAlex

Blood-based biomarkers for Alzheimer's disease: towards clinical implementation

📅 Nov 2021 👤 Charlotte E Teunissen, Inge M W Verberk, Elisabeth H Thijssen et al. 📊 965 citations

This research explores Blood-based biomarkers for Alzheimer's disease: towards clin..., contributing new insights to the field of Medicine & Biology.

🧬 Medicine & Biology OpenAlex

Global prevalence of sarcopenia and severe sarcopenia: a systematic review and meta‐analysis

📅 Nov 2021 👤 Fanny Petermann‐Rocha, Viktoria Balntzi, Stuart R. Gray et al. 📊 1,397 citations

BACKGROUND: Sarcopenia is defined as the loss of muscle mass and strength. CONCLUSIONS: The prevalence of sarcopenia and severe sarcopenia varied considerably according to the classification and cut-o...

🧬 Medicine & Biology OpenAlex

Anti-obesity drug discovery: advances and challenges

📅 Nov 2021 👤 Timo D. Müller, Matthias Blüher, Matthias H. Tschöp et al. 📊 962 citations

This research explores Anti-obesity drug discovery: advances and challenges, contributing new insights to the field of Medicine & Biology.

🧬 Medicine & Biology OpenAlex

The 2021 WHO Classification of Lung Tumors: Impact of Advances Since 2015

📅 Nov 2021 👤 Andrew G. Nicholson, Ming‐Sound Tsao, Mary Beth Beasley et al. 📊 1,467 citations

This research explores 2021 WHO Classification of Lung Tumors: Impact of Advances S..., contributing new insights to the field of Medicine & Biology.

🧬 Medicine & Biology PubMed

Predicting changes in osmolality.

📅 Nov 2021 👤 Yang Zhe, Wang Tongtong, Oka Yuki

Two neural circuits control the release of vasopressin in response to eating and drinking before there are any detectable changes in blood water levels.

🧬 Medicine & Biology OpenAlex

Multivariable association discovery in population-scale meta-omics studies

📅 Nov 2021 👤 Himel Mallick, Ali Rahnavard, Lauren J. McIver et al. 📊 2,421 citations

It is challenging to associate features such as human health outcomes, diet, environmental conditions, or other metadata to microbial community measurements, due in part to their quantitative properti...

🧬 Medicine & Biology OpenAlex

Global Epidemiology of Stroke and Access to Acute Ischemic Stroke Interventions

📅 Nov 2021 👤 Vasu Saini, Luis Guada, Dileep R. Yavagal 📊 1,313 citations

PURPOSE OF THE REVIEW: To provide an up-to-date review of the incidence of stroke and large vessel occlusion (LVO) around the globe, as well as the eligibility and access to IV thrombolysis (IVT) and...

🧬 Medicine & Biology OpenAlex

KRAS mutation: from undruggable to druggable in cancer

📅 Nov 2021 👤 Lamei Huang, Zhixing Guo, Fang Wang et al. 📊 1,048 citations

Cancer is the leading cause of death worldwide, and its treatment and outcomes have been dramatically revolutionised by targeted therapies. This review summarises the most recent understanding of fund...

🧬 Medicine & Biology OpenAlex

STROCSS 2021: Strengthening the reporting of cohort, cross-sectional and case-control studies in sur...

📅 Nov 2021 👤 Ginimol Mathew, Riaz Agha, Joerg Albrecht et al. 📊 2,135 citations

INTRODUCTION: Strengthening The Reporting Of Cohort Studies in Surgery (STROCSS) guidelines were developed in 2017 in order to improve the reporting quality of observational studies in surgery and upd...

🧬 Medicine & Biology OpenAlex

Immunotherapies for hepatocellular carcinoma

📅 Nov 2021 👤 Josep M. Llovet, Florian Castet, Mathias Heikenwälder et al. 📊 1,795 citations

This research explores Immunotherapies for hepatocellular carcinoma, contributing new insights to the field of Medicine & Biology.

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