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Global Epidemiology of Stroke and Access to Acute Ischemic Stroke Interventions

📅 November 16, 2021 👤 Vasu Saini, Luis Guada, Dileep R. Yavagal 📖 Neurology 📊 1,313 citations

🤖 Plain-English Summary

PURPOSE OF THE REVIEW: To provide an up-to-date review of the incidence of stroke and large vessel occlusion (LVO) around the globe, as well as the eligibility and access to IV thrombolysis (IVT) and mechanical thrombectomy (MT) worldwide. This highlights the large gap among eligible patients and the low utilization rates of these advances across the globe.

🔑 Key Findings

  • RECENT FINDINGS: Randomized clinical trials have established MT with or without IVT as the usual care for patients with LVO stroke for up to 24 hours from symptom onset.
  • Eligibility for IVT has extended beyond 4.5 hours based on permissible imaging criteria.
  • With these advances in the last 5 years, there has been a notable increase in the population of patients eligible for acute stroke interventions.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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📋 Article Details

Category 🧬 Medicine & Biology
Published Nov 16, 2021
Journal Neurology
Authors Vasu Saini, Luis Guada, Dileep R. Yavagal
DOI 10.1212/wnl.0000000000012781
Citations 1,313
Source OpenAlex

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