Research Article Hub

Explore the latest peer-reviewed research with AI-generated summaries, key findings, and insights for easy understanding. All content is legally sourced from academic metadata with links to original papers.

2,222Articles
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🧬 Medicine & Biology OpenAlex

Impact of heavy metals on the environment and human health: Novel therapeutic insights to counter th...

📅 Jan 2022 👤 Saikat Mitra, Arka Chakraborty, Abu Montakim Tareq et al. 📊 1,948 citations

Heavy metals are well-known environmental pollutants owing to their toxicity, longevity in the atmosphere, and ability to accumulate in the human body via bioaccumulation. Therefore this review aimed...

🧬 Medicine & Biology PubMed

Computational Genomics in the Era of Precision Medicine: Applications to Variant Analysis and Gene T...

📅 Jan 2022 👤 Wang Yung-Chun, Wu Yuchang, Choi Julie et al.

Rapid methodological advances in statistical and computational genomics have enabled researchers to better identify and interpret both rare and common variants responsible for complex human diseases....

🧬 Medicine & Biology OpenAlex

Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis

📅 Jan 2022 👤 Steven R. Ytterberg, Deepak L. Bhatt, Ted R. Mikuls et al. 📊 1,686 citations

BACKGROUND: Increases in lipid levels and cancers with tofacitinib prompted a trial of major adverse cardiovascular events (MACE) and cancers in patients with rheumatoid arthritis receiving tofacitini...

🧬 Medicine & Biology OpenAlex

Multiple early factors anticipate post-acute COVID-19 sequelae

📅 Jan 2022 👤 Yapeng Su, Dan Yuan, Daniel Chen et al. 📊 1,185 citations

T cells exhibited unique dynamics during recovery from COVID-19. We find that immunological associations between PASC factors diminish over time, leading to distinct convalescent immune states.

🧬 Medicine & Biology OpenAlex

Risk assessment of microplastic particles

📅 Jan 2022 👤 Albert A. Koelmans, Paula E. Redondo‐Hasselerharm, Nur Hazimah Mohamed Nor et al. 📊 1,026 citations

This research explores Risk assessment of microplastic particles, contributing new insights to the field of Medicine & Biology.

🧬 Medicine & Biology OpenAlex

Terpenes and terpenoids as main bioactive compounds of essential oils, their roles in human health a...

📅 Jan 2022 👤 Ayu Masyita, Reka Mustika Sari, Ayun Dwi Astuti et al. 📊 970 citations

Essential oils (EOs) are volatile and concentrated liquids extracted from different parts of plants. Available literature confirms that EOs exhibit antimicrobial and food preservative properties that...

🧬 Medicine & Biology OpenAlex

PROTAC targeted protein degraders: the past is prologue

📅 Jan 2022 👤 Miklós Békés, David R. Langley, Craig M. Crews 📊 3,009 citations

This research explores PROTAC targeted protein degraders: the past is prologue, contributing new insights to the field of Medicine & Biology.

🧬 Medicine & Biology OpenAlex

Receiver operating characteristic curve: overview and practical use for clinicians

📅 Jan 2022 👤 Francis Sahngun Nahm 📊 1,400 citations

Using diagnostic testing to determine the presence or absence of a disease is essential in clinical practice. Although clinicians who do not have expertise in statistics do not need to understand both...

🧬 Medicine & Biology OpenAlex

Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple scleros...

📅 Jan 2022 👤 Kjetil Bjørnevik, Marianna Cortese, Brian C. Healy et al. 📊 1,971 citations

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system of unknown etiology. Serum levels of neurofilament light chain, a biomarker of neuroaxonal degener...

🧬 Medicine & Biology OpenAlex

Review on Methylene Blue: Its Properties, Uses, Toxicity and Photodegradation

📅 Jan 2022 👤 Idrees Khan, Khalid Saeed, Ivar Zekker et al. 📊 1,542 citations

The unavailability of clean drinking water is one of the significant health issues in modern times. An overview of the future perspectives to utilize MB at an industrial scale is also provided.

🧬 Medicine & Biology OpenAlex

Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infect...

📅 Jan 2022 👤 Chansavath Phetsouphanh, D.R. Darley, Daniel B. Wilson et al. 📊 995 citations

This research explores Immunological dysfunction persists for 8 months following in..., contributing new insights to the field of Medicine & Biology.

🧬 Medicine & Biology OpenAlex

Metabolic Syndrome: Updates on Pathophysiology and Management in 2021

📅 Jan 2022 👤 Gracia Fahed, Laurence Aoun, Morgan Bou Zerdan et al. 📊 1,371 citations

Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin resistance, atherogenic dyslipidemia, central obesity, and hypertension. We also discuss the current and latest...

🧬 Medicine & Biology OpenAlex

A critical review on the treatment of dye-containing wastewater: Ecotoxicological and health concern...

📅 Jan 2022 👤 Rania Al-Tohamy, Sameh S. Ali, Fanghua Li et al. 📊 3,125 citations

The synthetic dyes used in the textile industry pollute a large amount of water. This review compares the most recent technologies which are commonly used to remove dye from textile wastewater, with a...

🧬 Medicine & Biology OpenAlex

Harnessing protein folding neural networks for peptide–protein docking

📅 Jan 2022 👤 Tomer Tsaban, Julia K. Varga, Orly Avraham et al. 📊 1,189 citations

Highly accurate protein structure predictions by deep neural networks such as AlphaFold2 and RoseTTAFold have tremendous impact on structural biology and beyond. We explore what AlphaFold2 has memoriz...

🧬 Medicine & Biology OpenAlex

Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa

📅 Jan 2022 👤 Raquel Viana, Sikhulile Moyo, Daniel G. Amoako et al. 📊 1,895 citations

Abstract The SARS-CoV-2 epidemic in southern Africa has been characterized by three distinct waves. The Omicron variant is exceptional for carrying over 30 mutations in the spike glycoprotein, which a...

🧬 Medicine & Biology OpenAlex

Harnessing cytokines and chemokines for cancer therapy

📅 Jan 2022 👤 David Propper, Frances R. Balkwill 📊 987 citations

This research explores Harnessing cytokines and chemokines for cancer therapy, contributing new insights to the field of Medicine & Biology.

🧬 Medicine & Biology OpenAlex

CAR T cells produced in vivo to treat cardiac injury

📅 Jan 2022 👤 Joel G. Rurik, István Tombácz, Amir Yadegari et al. 📊 1,231 citations

Fibrosis affects millions of people with cardiac disease. Treatment with modified mRNA-targeted LNPs reduced fibrosis and restored cardiac function after injury.

🧬 Medicine & Biology OpenAlex

Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial

📅 Jan 2022 👤 Peter B. Gilbert, David C. Montefiori, Adrian B. McDermott et al. 📊 1,199 citations

In the coronavirus efficacy (COVE) phase 3 clinical trial, vaccine recipients were assessed for neutralizing and binding antibodies as correlates of risk for COVID-19 disease and as correlates of prot...

🧬 Medicine & Biology OpenAlex

mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant

📅 Jan 2022 👤 Wilfredo F. García-Beltrán, Kerri St. Denis, Angelique Hoelzemer et al. 📊 1,091 citations

This research explores mRNA-based COVID-19 vaccine boosters induce neutralizing imm..., contributing new insights to the field of Medicine & Biology.

🧬 Medicine & Biology OpenAlex

Relatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma

📅 Jan 2022 👤 Hussein A. Tawbi, Dirk Schadendorf, Evan J. Lipson et al. 📊 1,742 citations

BACKGROUND: Lymphocyte-activation gene 3 (LAG-3) and programmed death 1 (PD-1) are distinct inhibitory immune checkpoints that contribute to T-cell exhaustion. Relatlimab and nivolumab in combination...

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