Explore the latest peer-reviewed research with AI-generated summaries, key findings, and insights for easy understanding. All content is legally sourced from academic metadata with links to original papers.
Monkeypox, a zoonotic disease caused by an orthopoxvirus, results in a smallpox-like disease in humans. The appearance of outbreaks beyond Africa highlights the global relevance of the disease.
Ninety percent of clinical drug development fails despite implementation of many successful strategies, which raised the question whether certain aspects in target validation and drug optimization are...
This research explores Mendelian randomization, contributing new insights to the field of Medicine & Biology.
BACKGROUND: The addition of pembrolizumab to neoadjuvant chemotherapy led to a significantly higher percentage of patients with early triple-negative breast cancer having a pathological complete respo...
Heart Failure (HF) is a multi-faceted and life-threatening syndrome characterized by significant morbidity and mortality, poor functional capacity and quality of life, and high costs. There is substan...
The cardiovascular complications of acute coronavirus disease 2019 (COVID-19) are well described, but the post-acute cardiovascular manifestations of COVID-19 have not yet been comprehensively charact...
The RNA binding protein FMRP regulates the synthesis of synaptic and nuclear proteins within different compartments of a neuron.
PURPOSE The phase III PACIFIC trial compared durvalumab with placebo in patients with unresectable, stage III non–small-cell lung cancer and no disease progression after concurrent chemoradiotherapy....
BACKGROUND: First-line chemotherapy for advanced esophageal squamous-cell carcinoma results in poor outcomes. CONCLUSIONS: Both first-line treatment with nivolumab plus chemotherapy and first-line tre...
The gut microbiota is now considered as one of the key elements contributing to the regulation of host health. Numerous molecular mechanisms explaining how gut bacteria might be causally linked with t...
Gastric cancer is the third leading cause of cancer-related deaths worldwide. Multidisciplinary team management is essential for all patients with localized gastric cancer.
This research explores T cell immune response against SARS-CoV-2, contributing new insights to the field of Medicine & Biology.
BACKGROUND: Intimate partner violence against women is a global public health problem with many short-term and long-term effects on the physical and mental health of women and their children. There is...
This research explores Adipose-tissue plasticity in health and disease, contributing new insights to the field of Medicine & Biology.
IMPORTANCE: Multiple myeloma is a hematologic malignancy characterized by presence of abnormal clonal plasma cells in the bone marrow, with potential for uncontrolled growth causing destructive bone l...
With the advent of genome-wide screening methods-beginning with microarray technologies and moving onto next generation sequencing methods-the era of precision and personalized medicine was born. We s...
Digital transformation is currently impacting not only health care but also education curricula for medicine and life sciences. This expert review offers an analysis of the bottlenecks that affect and...
Telemedicine is a disruptive innovation in the health care marketplace that holds the potential for transforming medicine by improving access to medical care and providing a more affordable way of del...
As the era of big data transforms modern medicine, clinicians have access to more health data than ever. Debates about how and when to institutionalize ignorance of health data are not unique to clini...
Opportunity is the essence of a career in science or medicine and this continues to be a major source of satisfaction for the many scientists and health care providers worldwide. I could not have been...