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Therapeutic peptides: current applications and future directions

📅 February 14, 2022 👤 Lei Wang, Nanxi Wang, Wenping Zhang et al. 📖 Signal Transduction and Targeted Therapy 📊 1,951 citations

🤖 Plain-English Summary

Peptide drug development has made great progress in the last decade thanks to new production, modification, and analytic technologies. This review summarizes the efforts and achievements in peptide drug discovery, production, and modification, and their current applications.

🔑 Key Findings

  • Peptides have been produced and modified using both chemical and biological methods, together with novel design and delivery strategies, which have helped to overcome the inherent drawbacks of peptides and have allowed the continued advancement of this field.
  • A wide variety of natural and modified peptides have been obtained and studied, covering multiple therapeutic areas.
  • This review summarizes the efforts and achievements in peptide drug discovery, production, and modification, and their current applications.

💡 Why This Matters

These innovations can translate to real-world improvements in technology, infrastructure, and everyday tools.

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📋 Article Details

Category ⚙️ Engineering & Technology
Published Feb 14, 2022
Journal Signal Transduction and Targeted Therapy
Authors Lei Wang, Nanxi Wang, Wenping Zhang, Xurui Cheng, Zhibin Yan
DOI 10.1038/s41392-022-00904-4
Citations 1,951
Source OpenAlex

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