ColabFold: making protein folding accessible to all

🤖 Plain-English Summary

ColabFold offers accelerated prediction of protein structures and complexes by combining the fast homology search of MMseqs2 with AlphaFold2 or RoseTTAFold. Coupled with Google Colaboratory, ColabFold becomes a free and accessible platform for protein folding.

🔑 Key Findings

• ColabFold's 40-60-fold faster search and optimized model utilization enables prediction of close to 1,000 structures per day on a server with one graphics processing unit.
• Coupled with Google Colaboratory, ColabFold becomes a free and accessible platform for protein folding.
• ColabFold is open-source software available at https://github.com/sokrypton/ColabFold and its novel environmental databases are available at https://colabfold.mmseqs.com .

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