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The evolution of developmental biology through conceptual and technological revolutions.

📅 July 11, 2024 👤 Liberali Prisca, Schier Alexander F 📖 Cell

🤖 Plain-English Summary

Developmental biology-the study of the processes by which cells, tissues, and organisms develop and change over time-has entered a new golden age. We discuss the connections of development with evolution, self-organization, metabolism, time, and ecology.

🔑 Key Findings

  • After the molecular genetics revolution in the 80s and 90s and the diversification of the field in the early 21st century, we have entered a phase when powerful technologies provide new approaches and open unexplored avenues.
  • Progress in the field has been accelerated by advances in genomics, imaging, engineering, and computational biology and by emerging model systems ranging from tardigrades to organoids.
  • We summarize how revolutionary technologies have led to remarkable progress in understanding animal development.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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