ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease

🤖 Plain-English Summary

Gastroesophageal reflux disease (GERD) continues to be among the most common diseases seen by gastroenterologists, surgeons, and primary care physicians. The Grading of Recommendations, Assessment, Development, and Evaluation system was used to evaluate the evidence and the strength of recommendations.

🔑 Key Findings

• Our understanding of the varied presentations of GERD, enhancements in diagnostic testing, and approach to patient management have evolved.
• During this time, scrutiny of proton pump inhibitors (PPIs) has increased considerably.
• Although PPIs remain the medical treatment of choice for GERD, multiple publications have raised questions about adverse events, raising doubts about the safety of long-term use and increasing concern about overprescribing of PPIs.

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