Explore the latest peer-reviewed research with AI-generated summaries, key findings, and insights for easy understanding. All content is legally sourced from academic metadata with links to original papers.
BACKGROUND: Among breast cancers without human epidermal growth factor receptor 2 (HER2) amplification, overexpression, or both, a large proportion express low levels of HER2 that may be targetable. C...
BACKGROUND: Neoadjuvant chemotherapy and radiation followed by surgical resection of the rectum is a standard treatment for locally advanced rectal cancer. Longer follow-up is needed to assess the dur...
BACKGROUND: Teclistamab is a T-cell-redirecting bispecific antibody that targets both CD3 expressed on the surface of T cells and B-cell maturation antigen expressed on the surface of myeloma cells. C...
Background & AimsThe aim of this study was to provide an overview of the burden of esophageal cancer in 185 countries in 2020 and projections for the year 2040.MethodsEstimates of esophageal cancer ca...
BACKGROUND: The role of adjuvant chemotherapy in stage II colon cancer continues to be debated. CONCLUSIONS: A ctDNA-guided approach to the treatment of stage II colon cancer reduced adjuvant chemothe...
BACKGROUND: , locking it in its inactive state. CONCLUSIONS: -mutated NSCLC, adagrasib showed clinical efficacy without new safety signals.
Since the publication of the Revised European-American Classification of Lymphoid Neoplasms in 1994, subsequent updates of the classification of lymphoid neoplasms have been generated through iterativ...
BACKGROUND: Patients with advanced biliary tract cancer have a poor prognosis, and first-line standard of care (gemcitabine plus cisplatin) has remained unchanged for more than 10 years. The safety pr...
The therapeutic options for patients with noninvasive or invasive breast cancer are complex and varied. The content featured in this issue focuses on the recommendations for overall management of duct...
Implementation of personalized medicine in the clinic is a lengthy and multifaceted approach that is also dependent on the raising of the general public's awareness of genomics. The Festival of Geneti...
There is an ongoing need for novel biomarkers in clinical neuroscience, as diagnosis of neurological and psychiatric disorders is hampered by the pronounced overlap of behavioral symptoms and other pa...
The path to completion of the functional annotation of the haploid human genome reference build, exploration of the clan genomics hypothesis, understanding human gene and genome functional biology, an...
Immunology and reproduction are intimately combined in human physiology; however, the mechanisms whereby the uterus accepts the fetus and allows it to flourish remain unclear, at least in the human. T...
This research explores Akkermansia muciniphila: paradigm for next-generation benefi..., contributing new insights to the field of Medicine & Biology.
Introduction PART ONE: WHERE ARE THE WOMEN MANAGERS?
The response rates of online surveys were often examined in the literature by comparing to other modes of surveys. Other factors that impacted the rates included the funding status of a project, and t...
OBJECTIVE: To investigate the association between gestational diabetes mellitus and adverse outcomes of pregnancy after adjustment for at least minimal confounding factors. Future primary studies shou...
Oxidative stress has been linked with a variety of diseases, being involved in the debut and/or progress of several neurodegenerative disorders. Nonetheless, there are still several mechanisms that ne...
This research explores Clinical features and management of human monkeypox: a retro..., contributing new insights to the field of Medicine & Biology.
The Lancet Commission on pollution and health reported that pollution was responsible for 9 million premature deaths in 2015, making it the world's largest environmental risk factor for disease and pr...