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Toward defining the clinically actionable genome of metastatic breast cancer.

📅 December 9, 2022 👤 Fröhling Stefan 📖 Med (New York, N.Y.)

🤖 Plain-English Summary

Genomics-guided therapies are transforming oncology, but selecting patients who are candidates for drugs matched to their tumor's biological profile is difficult.

🔑 Key Findings

  • have shown in a randomized clinical trial that a standardized system for determining the actionability of genomic alterations identifies breast cancer patients who significantly benefit from molecularly targeted agents.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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📋 Article Details

Category 🧬 Medicine & Biology
Published Dec 09, 2022
Journal Med (New York, N.Y.)
Authors Fröhling Stefan
DOI 10.1016/j.medj.2022.11.004
Source PubMed

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