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The neuroscience in breast cancer: Current insights and clinical opportunities.

📅 February 15, 2025 👤 Wang Jia-Feng, Wang Meng-Chuan, Jiang Lei-Lei et al. 📖 Heliyon

🤖 Plain-English Summary

The involvement of nerves in the development of breast cancer has emerged as a significant factor. Additionally, the study discussed the potential of nerves as biomarkers for diagnosing and prognosticating breast cancer, and evaluated prospects for improving chemotherapy and immunotherapy therapeutic outcomes in breast cancer treatment.

🔑 Key Findings

  • Interaction between the nervous system and breast cancer can influence tumor initiation, growth, invasion, metastasis, reverse resistance to drugs, promote inflammation in tumors, and impair the immune system's ability to combat cancer.
  • This review examined the intricate relationship linking the nervous system with breast cancer, emphasizing both central and peripheral aspects of the nervous system.
  • Moreover, we reviewed neural cell factors and their impact on breast cancer progression, alongside the interactions between nerves and immunology, microbiota in breast cancer.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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📋 Article Details

Category 🧬 Medicine & Biology
Published Feb 15, 2025
Journal Heliyon
Authors Wang Jia-Feng, Wang Meng-Chuan, Jiang Lei-Lei, Lin Neng-Ming
DOI 10.1016/j.heliyon.2025.e42293
Source PubMed

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