SynergyFinder Plus: Toward Better Interpretation and Annotation of Drug Combination Screening Datasets

🤖 Plain-English Summary

Combinatorial therapies have been recently proposed to improve the efficacy of anticancer treatment. These annotations will improve the interpretation of the mechanisms of action of drug combinations.

🔑 Key Findings

• The SynergyFinder R package is a software used to analyze pre-clinical drug combination datasets.
• Here, we report the major updates to the SynergyFinder R package for improved interpretation and annotation of drug combination screening results.
• Unlike the existing implementations, the updated SynergyFinder R package includes five main innovations.

🔗 Related Resources