Safe and effective genomic medicine implementation in hospitals: a scoping review.

🤖 Plain-English Summary

Genomic medicine is rapidly changing routine clinical care in a range of specialties. Our results can contribute to the design of an approach which supports hospital planning and decision-making by integrating all elements of clinical governance.

🔑 Key Findings

• Effective clinical governance is essential for safe implementation of emerging clinical practice, including genomic medicine.
• Frameworks exist for national implementation of genomics but lack the granularity needed by hospitals to guide local implementation of national policy.We aimed to identify if a framework suitable to support the safe, effective implementation and use of genomic medicine at a hospital level exists.
• A systematic search using scoping review methodology was performed, searching three databases (Medline, Embase and PubMed), from 2009 to 2022, to identify structured approaches to the clinical governance of genomics at a meso (hospital/hospital consortia) level.

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