Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease

🤖 Plain-English Summary

BACKGROUND: The prognoses with respect to mortality and hepatic and nonhepatic outcomes across the histologic spectrum of nonalcoholic fatty liver disease (NAFLD) are not well defined. CONCLUSIONS: In this prospective study involving patients with NAFLD, fibrosis stages F3 and F4 were associated with increased risks of liver-related complications and death.

🔑 Key Findings

• METHODS: We prospectively followed a multicenter patient population that included the full histologic spectrum of NAFLD.
• The incidences of death and other outcomes were compared across baseline histologic characteristics.
• RESULTS: A total of 1773 adults with NAFLD were followed for a median of 4 years.

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