Pancreatic Cancer

🤖 Plain-English Summary

Importance: Pancreatic ductal adenocarcinoma (PDAC) is a relatively uncommon cancer, with approximately 60 430 new diagnoses expected in 2021 in the US. Currently available cytotoxic therapies for advanced disease are modestly effective.

🔑 Key Findings

• The incidence of PDAC is increasing by 0.5% to 1.0% per year, and it is projected to become the second-leading cause of cancer-related mortality by 2030.
• Observations: Effective screening is not available for PDAC, and most patients present with locally advanced (30%-35%) or metastatic (50%-55%) disease at diagnosis.
• A multidisciplinary management approach is recommended.

🔗 Related Resources