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Obstructive Sleep Apnea and Cardiovascular Disease: A Scientific Statement From the American Heart Association

📅 June 21, 2021 👤 Yerem Yeghiazarians, Hani Jneid, Jeremy Tietjens et al. 📖 Circulation 📊 1,291 citations

🤖 Plain-English Summary

Obstructive sleep apnea (OSA) is characterized by recurrent complete and partial upper airway obstructive events, resulting in intermittent hypoxemia, autonomic fluctuation, and sleep fragmentation. Continuous positive airway pressure should be offered to patients with severe OSA, whereas oral appliances can be considered for those with mild to moderate OSA or for continuous positive airway pressure-intolerant patients.

🔑 Key Findings

  • Approximately 34% and 17% of middle-aged men and women, respectively, meet the diagnostic criteria for OSA.
  • Sleep disturbances are common and underdiagnosed among middle-aged and older adults, and the prevalence varies by race/ethnicity, sex, and obesity status.
  • OSA prevalence is as high as 40% to 80% in patients with hypertension, heart failure, coronary artery disease, pulmonary hypertension, atrial fibrillation, and stroke.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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📋 Article Details

Category 🧬 Medicine & Biology
Published Jun 21, 2021
Journal Circulation
Authors Yerem Yeghiazarians, Hani Jneid, Jeremy Tietjens, Susan Redline, Devin L. Brown
DOI 10.1161/cir.0000000000000988
Citations 1,291
Source OpenAlex

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