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Neutrophil to Lymphocyte Ratio: An Emerging Marker of the Relationships between the Immune System and Diseases

📅 March 26, 2022 👤 Agata Buonacera, Benedetta Stancanelli, Michele Colaci et al. 📖 International Journal of Molecular Sciences 📊 958 citations

🤖 Plain-English Summary

Over the last 10 years, the evaluation of the neutrophil-to-lymphocyte ratio (NLR) as an emerging marker of diseases has become a compelling field of bio-medical research. Moreover, NLR was recently considered as part of the decision-making processes concerning the admission/recovery of patients with COVID-19 pneumonia.

🔑 Key Findings

  • Although a precise and unique cut-off value has not been yet found, its role as a flag of immune system homeostasis is well established.
  • NLR has a well-known prognostic value and independently correlates with mortality in the general population and in several specific subsets of disease (sepsis, pneumonia, COVID-19, cancer, etc.).
  • Moreover, NLR was recently considered as part of the decision-making processes concerning the admission/recovery of patients with COVID-19 pneumonia.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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📋 Article Details

Category 🧬 Medicine & Biology
Published Mar 26, 2022
Journal International Journal of Molecular Sciences
Authors Agata Buonacera, Benedetta Stancanelli, Michele Colaci, Lorenzo Malatino
DOI 10.3390/ijms23073636
Citations 958
Source OpenAlex

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