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Microaxial Flow Pump or Standard Care in Infarct-Related Cardiogenic Shock

📅 April 7, 2024 👤 Jacob Eifer Møller, Thomas Engstrøm, Lisette Okkels Jensen et al. 📖 New England Journal of Medicine 📊 818 citations

🤖 Plain-English Summary

BACKGROUND: The effects of temporary mechanical circulatory support with a microaxial flow pump on mortality among patients with ST-segment elevation myocardial infarction (STEMI) complicated by cardiogenic shock remains unclear. The incidence of a composite of adverse events was higher with the use of the microaxial flow pump.

🔑 Key Findings

  • METHODS: In an international, multicenter, randomized trial, we assigned patients with STEMI and cardiogenic shock to receive a microaxial flow pump (Impella CP) plus standard care or standard care alone.
  • The primary end point was death from any cause at 180 days.
  • A composite safety end point was severe bleeding, limb ischemia, hemolysis, device failure, or worsening aortic regurgitation.

💡 Why This Matters

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📋 Article Details

Category ⚛️ Physics & Space Science
Published Apr 07, 2024
Journal New England Journal of Medicine
Authors Jacob Eifer Møller, Thomas Engstrøm, Lisette Okkels Jensen, Hans Eiskjær, Norman Mangner
DOI 10.1056/nejmoa2312572
Citations 818
Source OpenAlex

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