Lobar or Sublobar Resection for Peripheral Stage IA Non–Small-Cell Lung Cancer

🤖 Plain-English Summary

BACKGROUND: The increased detection of small-sized peripheral non-small-cell lung cancer (NSCLC) has renewed interest in sublobar resection in lieu of lobectomy. Overall survival was similar with the two procedures.

🔑 Key Findings

• METHODS: We conducted a multicenter, noninferiority, phase 3 trial in which patients with NSCLC clinically staged as T1aN0 (tumor size, ≤2 cm) were randomly assigned to undergo sublobar resection or lobar resection after intraoperative confirmation of node-negative disease.
• The primary end point was disease-free survival, defined as the time between randomization and disease recurrence or death from any cause.
• Secondary end points were overall survival, locoregional and systemic recurrence, and pulmonary functions.

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