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Inequalities and Inclusion in Genomics Applied to Healthcare: A Latin American Perspective.

📅 August 1, 2025 👤 Lopes-Cendes Iscia, de Oliveira Thais C 📖 Annual review of genomics and human genetics

🤖 Plain-English Summary

Integrating genomics into healthcare within the precision medicine (PM) framework poses distinct challenges in resource-limited regions like Latin America and the Caribbean (LAC). Despite these challenges, current regional efforts showcase the feasibility of integrating genomics in LAC and highlight the importance of expanded collaborations.

🔑 Key Findings

  • These challenges arise partly from the lack of PM models tailored for low- and middle-income countries.
  • To address this, healthcare authorities in LAC should adopt predictive models to estimate costs and infrastructure needed for PM programs.
  • The predominance of admixed populations in LAC adds complexity, given their underrepresentation in genomic studies.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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📋 Article Details

Category 🧬 Medicine & Biology
Published Aug 01, 2025
Journal Annual review of genomics and human genetics
Authors Lopes-Cendes Iscia, de Oliveira Thais C
DOI 10.1146/annurev-genom-111224-100329
Source PubMed

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