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GTDB: an ongoing census of bacterial and archaeal diversity through a phylogenetically consistent, rank normalized and complete genome-based taxonomy

📅 September 8, 2021 👤 Donovan H. Parks, Maria Chuvochina, Christian Rinke et al. 📖 Nucleic Acids Research 📊 2,448 citations

🤖 Plain-English Summary

The Genome Taxonomy Database (GTDB; https://gtdb.ecogenomic.org) provides a phylogenetically consistent and rank normalized genome-based taxonomy for prokaryotic genomes sourced from the NCBI Assembly database. Methodological updates and policy changes made since the inception of the GTDB are then described along with the procedure used to update species clusters in the GTDB.

🔑 Key Findings

  • GTDB R06-RS202 spans 254 090 bacterial and 4316 archaeal genomes, a 270% increase since the introduction of the GTDB in November, 2017.
  • These genomes are organized into 45 555 bacterial and 2339 archaeal species clusters which is a 200% increase since the integration of species clusters into the GTDB in June, 2019.
  • Here, we explore prokaryotic diversity from the perspective of the GTDB and highlight the importance of metagenome-assembled genomes in expanding available genomic representation.

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📋 Article Details

Category ∑ Mathematics
Published Sep 08, 2021
Journal Nucleic Acids Research
Authors Donovan H. Parks, Maria Chuvochina, Christian Rinke, Aaron J. Mussig, Pierre-Alain Chaumeil
DOI 10.1093/nar/gkab776
Citations 2,448
Source OpenAlex

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