Global colorectal cancer burden in 2020 and projections to 2040

🤖 Plain-English Summary

As the third most common malignancy and the second most deadly cancer, colorectal cancer (CRC) induces estimated 1.9 million incidence cases and 0.9 million deaths worldwide in 2020. An accurate CRC subtype classification system is of great significance for basic research and clinical outcome.

🔑 Key Findings

• The incidence of CRC is higher in highly developed countries, and it is increasing in middle- and low-income countries due to westernization.
• Moreover, a rising incidence of early-onset CRC is also emerging.
• The large number of CRC cases poses a growing global public health challenge.

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