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Genomics and multiomics in the age of precision medicine.

📅 March 1, 2025 👤 Mani Srinivasan, Lalani Seema R, Pammi Mohan 📖 Pediatric research

🤖 Plain-English Summary

Precision medicine is a transformative healthcare model that utilizes an understanding of a person's genome, environment, lifestyle, and interplay to deliver customized healthcare. Phenomenal advancements in bioinformatics, data sciences, and artificial intelligence have made integrative multiomics feasible and help us understand human health and disease better than any of them separately.

🔑 Key Findings

  • Precision medicine has the potential to improve the health and productivity of the population, enhance patient trust and satisfaction in healthcare, and accrue health cost-benefits both at an individual and population level.
  • Through faster and cost-effective genomics data, next-generation sequencing has provided us the impetus to understand the nuances of complex interactions between genes, diet, and lifestyle that are heterogeneous across the population.
  • The emergence of multiomics technologies, including transcriptomics, proteomics, epigenomics, metabolomics, and microbiomics, has enhanced the knowledge necessary for maximizing the applicability of genomics data for better health outcomes.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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📋 Article Details

Category 🧬 Medicine & Biology
Published Mar 01, 2025
Journal Pediatric research
Authors Mani Srinivasan, Lalani Seema R, Pammi Mohan
DOI 10.1038/s41390-025-04021-0
Source PubMed

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