Effect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital Cardiac Arrest

🤖 Plain-English Summary

Importance: Out-of-hospital cardiac arrest (OHCA) has poor outcome. However, the trial was possibly underpowered to detect a clinically relevant difference.

🔑 Key Findings

• Whether intra-arrest transport, extracorporeal cardiopulmonary resuscitation (ECPR), and immediate invasive assessment and treatment (invasive strategy) is beneficial in this setting remains uncertain.
• Objective: To determine whether an early invasive approach in adults with refractory OHCA improves neurologically favorable survival.
• Design, Setting, and Participants: Single-center, randomized clinical trial in Prague, Czech Republic, of adults with a witnessed OHCA of presumed cardiac origin without return of spontaneous circulation.

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