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Diabetic Foot Ulcers

📅 July 3, 2023 👤 David G. Armstrong, Tze‐Woei Tan, Andrew J.M. Boulton et al. 📖 JAMA 📊 1,374 citations

🤖 Plain-English Summary

Importance: Approximately 18.6 million people worldwide are affected by a diabetic foot ulcer each year, including 1.6 million people in the United States. Conclusions and Relevance: Diabetic foot ulcers affect approximately 18.6 million people worldwide each year and are associated with increased rates of amputation and death.

🔑 Key Findings

  • These ulcers precede 80% of lower extremity amputations among people diagnosed with diabetes and are associated with an increased risk of death.
  • Observations: Neurological, vascular, and biomechanical factors contribute to diabetic foot ulceration.
  • Approximately 50% to 60% of ulcers become infected, and about 20% of moderate to severe infections lead to lower extremity amputations.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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📋 Article Details

Category 🧬 Medicine & Biology
Published Jul 03, 2023
Journal JAMA
Authors David G. Armstrong, Tze‐Woei Tan, Andrew J.M. Boulton, Sicco A. Bus
DOI 10.1001/jama.2023.10578
Citations 1,374
Source OpenAlex

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