Controlled Drug Delivery Systems: Current Status and Future Directions

🤖 Plain-English Summary

The drug delivery system enables the release of the active pharmaceutical ingredient to achieve a desired therapeutic response. In addition, nano-drug delivery, targeted and smart drug delivery using stimuli-responsive and intelligent biomaterials is discussed with recent key findings.

🔑 Key Findings

• Conventional drug delivery systems (tablets, capsules, syrups, ointments, etc.) suffer from poor bioavailability and fluctuations in plasma drug level and are unable to achieve sustained release.
• Without an efficient delivery mechanism, the whole therapeutic process can be rendered useless.
• Moreover, the drug has to be delivered at a specified controlled rate and at the target site as precisely as possible to achieve maximum efficacy and safety.

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