Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics

🤖 Plain-English Summary

Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and produce aggressive malignancies that causes millions of deaths every year. Chemotherapeutic agents/pharmaceuticals served a great purpose over the past few decades and have remained the frontline choice for advanced-stage malignancies where surgery and/or radiation therapy cannot be prescribed due to specific reasons.

🔑 Key Findings

• With the new understanding of the molecular mechanism(s) of disease progression, our knowledge about the disease is snowballing, leading to the evolution of many new therapeutic regimes and their successive trials.
• In the past few decades, various combinations of therapies have been proposed and are presently employed in the treatment of diverse cancers.
• Targeted drug therapy, immunotherapy, and personalized medicines are now largely being employed, which were not common a few years back.

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