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Application of third-generation sequencing to herbal genomics.

📅 January 1, 2023 👤 Gao Longlong, Xu Wenjie, Xin Tianyi et al. 📖 Frontiers in plant science

🤖 Plain-English Summary

There is a long history of traditional medicine use. In addition, we summarize the nuclear and organelle genome assemblies of commonly used medicinal plants, choose several examples from genomics, transcriptomics, and molecular identification studies to dissect the specific processes and summarize the advantages and disadvantages of the two TGS techniques when applied to medicinal organisms.

🔑 Key Findings

  • However, little genetic information is available for the plants used in traditional medicine, which limits the exploitation of these natural resources.
  • Third-generation sequencing (TGS) techniques have made it possible to gather invaluable genetic information and develop herbal genomics.
  • In this review, we introduce two main TGS techniques, PacBio SMRT technology and Oxford Nanopore technology, and compare the two techniques against Illumina, the predominant next-generation sequencing technique.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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📋 Article Details

Category 🧬 Medicine & Biology
Published Jan 01, 2023
Journal Frontiers in plant science
Authors Gao Longlong, Xu Wenjie, Xin Tianyi, Song Jingyuan
DOI 10.3389/fpls.2023.1124536
Source PubMed

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