Antimicrobial peptides: mechanism of action, activity and clinical potential

🤖 Plain-English Summary

The management of bacterial infections is becoming a major clinical challenge due to the rapid evolution of antibiotic resistant bacteria. This comprehensive review provides a broad overview of AMPs from the origin, structural characteristics, mechanisms of action, biological activities to clinical applications.

🔑 Key Findings

• As an excellent candidate to overcome antibiotic resistance, antimicrobial peptides (AMPs) that are produced from the synthetic and natural sources demonstrate a broad-spectrum antimicrobial activity with the high specificity and low toxicity.
• These peptides possess distinctive structures and functions by employing sophisticated mechanisms of action.
• This comprehensive review provides a broad overview of AMPs from the origin, structural characteristics, mechanisms of action, biological activities to clinical applications.

🔗 Related Resources