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A review of radiomics and genomics applications in cancers: the way towards precision medicine.

📅 December 30, 2022 👤 Li Simin, Zhou Baosen 📖 Radiation oncology (London, England)

🤖 Plain-English Summary

The application of radiogenomics in oncology has great prospects in precision medicine. In this review, we summarized recent research on radiogenomics applications in solid cancers and presented the challenges impeding the adoption of radiomics in clinical practice.

🔑 Key Findings

  • Radiogenomics combines large volumes of radiomic features from medical digital images, genetic data from high-throughput sequencing, and clinical-epidemiological data into mathematical modelling.
  • The amalgamation of radiomics and genomics provides an approach to better study the molecular mechanism of tumour pathogenesis, as well as new evidence-supporting strategies to identify the characteristics of cancer patients, make clinical decisions by predicting prognosis, and improve the development of individualized treatment guidance.
  • In this review, we summarized recent research on radiogenomics applications in solid cancers and presented the challenges impeding the adoption of radiomics in clinical practice.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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📋 Article Details

Category 🧬 Medicine & Biology
Published Dec 30, 2022
Journal Radiation oncology (London, England)
Authors Li Simin, Zhou Baosen
DOI 10.1186/s13014-022-02192-2
Source PubMed

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