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A Review of Liposomes as a Drug Delivery System: Current Status of Approved Products, Regulatory Environments, and Future Perspectives

📅 February 17, 2022 👤 Peng Liu, Guiliang Chen, Jingchen Zhang 📖 Molecules 📊 1,233 citations

🤖 Plain-English Summary

Liposomes have been considered promising and versatile drug vesicles. Additionally, the current regulatory guidance and future perspectives related to liposomal products are summarized.

🔑 Key Findings

  • Compared with traditional drug delivery systems, liposomes exhibit better properties, including site-targeting, sustained or controlled release, protection of drugs from degradation and clearance, superior therapeutic effects, and lower toxic side effects.
  • Given these merits, several liposomal drug products have been successfully approved and used in clinics over the last couple of decades.
  • In this review, the liposomal drug products approved by the U.S.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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📋 Article Details

Category 🧬 Medicine & Biology
Published Feb 17, 2022
Journal Molecules
Authors Peng Liu, Guiliang Chen, Jingchen Zhang
DOI 10.3390/molecules27041372
Citations 1,233
Source OpenAlex

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