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A pilot retrospective study of a physician-directed and genomics-based model for precision lifestyle medicine.

📅 January 1, 2023 👤 Mallin Michael, Hall Jane, Herlihy Maria et al. 📖 Frontiers in medicine

🤖 Plain-English Summary

Precision lifestyle medicine is a relatively new field in primary care, based on the hypothesis that genetic predispositions influence an individual's response to specific interventions such as diet, exercise, and prescription medications. However, due to the inherent limitations of our observational study design and use of retrospective data, ongoing work will be crucial for continuing to shed light on the effectiveness of physician-led, genomics-based lifestyle coaching programs.

🔑 Key Findings

  • Despite the increase in commercially available genomic testing, few studies have investigated effects of a physician-directed program to optimize chronic disease using genomics-based precision medicine.
  • We performed an pilot, observational cohort study to evaluate effects of the Wild Health program, a physician and health coach service offering genomics-based lifestyle and medical interventions, on biomarkers indicative of chronic disease.
  • 871 patients underwent genomic testing, biomarker testing, and ongoing health coaching after initial medical consultation by a physician.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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📋 Article Details

Category 🧬 Medicine & Biology
Published Jan 01, 2023
Journal Frontiers in medicine
Authors Mallin Michael, Hall Jane, Herlihy Maria, Gelman Eduard J, Stone Michael B
DOI 10.3389/fmed.2023.1239737
Source PubMed

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