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A multisociety Delphi consensus statement on new fatty liver disease nomenclature

📅 June 22, 2023 👤 Mary E. Rinella, Jeffrey V. Lazarus, Vlad Ratziu et al. 📖 Hepatology 📊 2,867 citations

🤖 Plain-English Summary

The principal limitations of the terms NAFLD and NASH are the reliance on exclusionary confounder terms and the use of potentially stigmatising language. A new category, outside pure metabolic dysfunction-associated steatotic liver disease, termed metabolic and alcohol related/associated liver disease (MetALD), was selected to describe those with metabolic dysfunction-associated steatotic liver disease, who consume greater amounts of alcohol per week (140-350 g/wk and 210-420 g/wk for females an...

🔑 Key Findings

  • This study set out to determine if content experts and patient advocates were in favor of a change in nomenclature and/or definition.
  • A modified Delphi process was led by three large pan-national liver associations.
  • The consensus was defined a priori as a supermajority (67%) vote.

💡 Why This Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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📋 Article Details

Category 🧬 Medicine & Biology
Published Jun 22, 2023
Journal Hepatology
Authors Mary E. Rinella, Jeffrey V. Lazarus, Vlad Ratziu, Sven Francque, Arun J. Sanyal
DOI 10.1097/hep.0000000000000520
Citations 2,867
Source OpenAlex

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