A guide to the organ-on-a-chip

🤖 Plain-English Summary

Organs-on-chips (OoCs) are systems containing engineered or natural miniature tissues grown inside microfluidic chips. Organs-on-chips are microfluidic systems containing miniature tissues with the aim of mimicking human physiology for a range of biomedical and therapeutic applications.

🔑 Key Findings

• To better mimic human physiology, the chips are designed to control cell microenvironments and maintain tissue-specific functions.
• Combining advances in tissue engineering and microfabrication, OoCs have gained interest as a next-generation experimental platform to investigate human pathophysiology and the effect of therapeutics in the body.
• There are as many examples of OoCs as there are applications, making it difficult for new researchers to understand what makes one OoC more suited to an application than another.

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