A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex

🤖 Plain-English Summary

Klebsiella pneumoniae is a leading cause of antimicrobial-resistant (AMR) healthcare-associated infections, neonatal sepsis and community-acquired liver abscess, and is associated with chronic intestinal diseases. We also demonstrate the application of Kleborate to detect and type K.

🔑 Key Findings

• Its diversity and complex population structure pose challenges for analysis and interpretation of K.
• Here we introduce Kleborate, a tool for analysing genomes of K.
• pneumoniae and its associated species complex, which consolidates interrogation of key features of proven clinical importance.

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