JBrowse 2: a modular genome browser with views of synteny and structural variation

We present JBrowse 2, a general-purpose genome annotation browser offering enhanced visualization of complex structural variation and evolutionary relationships. These improvements are enabled by a ground-up redesign using modern web technology.

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• 1 It retains core features of JBrowse while adding new views for synteny, dotplots, breakpoints, gene fusions, and whole-genome overviews.
• 2 It allows users to share sessions, open multiple genomes, and navigate between views.
• 3 It can be embedded in a web page, used as a standalone application, or run from Jupyter notebooks or R sessions.

This work deepens our understanding of the fundamental laws governing the universe, from subatomic particles to cosmic structures.

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