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The changing epidemiology of human monkeypox—A potential threat? A systematic review

📅 Published: February 11, 2022 👤 Eveline M. Bunge, Bernard Hoet, Liddy Chen et al. 📖 PLoS neglected tropical diseases 📊 1,911 citations
AI-Generated Summary

Monkeypox, a zoonotic disease caused by an orthopoxvirus, results in a smallpox-like disease in humans. The appearance of outbreaks beyond Africa highlights the global relevance of the disease.

⚡ This is an original paraphrased summary — not copied from the abstract. Full paper available at the source link below.

Key Findings
  • 1 Since monkeypox in humans was initially diagnosed in 1970 in the Democratic Republic of the Congo (DRC), it has spread to other regions of Africa (primarily West and Central), and cases outside Africa have emerged in recent years.
  • 2 We conducted a systematic review of peer-reviewed and grey literature on how monkeypox epidemiology has evolved, with particular emphasis on the number of confirmed, probable, and/or possible cases, age at presentation, mortality, and geographical spread.
  • 3 The review is registered with PROSPERO (CRD42020208269).
Why It Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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