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Symptoms and risk factors for long COVID in non-hospitalized adults

📅 Published: July 25, 2022 👤 Anuradhaa Subramanian, Krishnarajah Nirantharakumar, Sarah Hughes et al. 📖 Nature Medicine 📊 1,128 citations
AI-Generated Summary

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is associated with a range of persistent symptoms impacting everyday functioning, known as post-COVID-19 condition or long COVID. The risk of developing long COVID was also found to be increased along a gradient of decreasing age.

⚡ This is an original paraphrased summary — not copied from the abstract. Full paper available at the source link below.

Key Findings
  • 1 We undertook a retrospective matched cohort study using a UK-based primary care database, Clinical Practice Research Datalink Aurum, to determine symptoms that are associated with confirmed SARS-CoV-2 infection beyond 12 weeks in non-hospitalized adults and the risk factors associated with developing persistent symptoms.
  • 2 We selected 486,149 adults with confirmed SARS-CoV-2 infection and 1,944,580 propensity score-matched adults with no recorded evidence of SARS-CoV-2 infection.
  • 3 Outcomes included 115 individual symptoms, as well as long COVID, defined as a composite outcome of 33 symptoms by the World Health Organization clinical case definition.
Why It Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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