Obesity: Epidemiology, Pathophysiology, and Therapeutics

Obesity is a complex multifactorial disease that accumulated excess body fat leads to negative effects on health. This review summarizes the global trends in obesity with a special focus on the pathogenesis of obesity from genetic factors to epigenetic factors, from social environmental factors to microenvironment factors.

⚡ This is an original paraphrased summary — not copied from the abstract. Full paper available at the source link below.

• 1 Obesity continues to accelerate resulting in an unprecedented epidemic that shows no significant signs of slowing down any time soon.
• 2 Raised body mass index (BMI) is a risk factor for noncommunicable diseases such as diabetes, cardiovascular diseases, and musculoskeletal disorders, resulting in dramatic decrease of life quality and expectancy.
• 3 The main cause of obesity is long-term energy imbalance between consumed calories and expended calories.

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

This summary is based on publicly available metadata and abstract. For the full research paper, visit the original source: