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Neutrophil to Lymphocyte Ratio: An Emerging Marker of the Relationships between the Immune System and Diseases

📅 Published: March 26, 2022 👤 Agata Buonacera, Benedetta Stancanelli, Michele Colaci et al. 📖 International Journal of Molecular Sciences 📊 958 citations
AI-Generated Summary

Over the last 10 years, the evaluation of the neutrophil-to-lymphocyte ratio (NLR) as an emerging marker of diseases has become a compelling field of bio-medical research. Moreover, NLR was recently considered as part of the decision-making processes concerning the admission/recovery of patients with COVID-19 pneumonia.

⚡ This is an original paraphrased summary — not copied from the abstract. Full paper available at the source link below.

Key Findings
  • 1 Although a precise and unique cut-off value has not been yet found, its role as a flag of immune system homeostasis is well established.
  • 2 NLR has a well-known prognostic value and independently correlates with mortality in the general population and in several specific subsets of disease (sepsis, pneumonia, COVID-19, cancer, etc.).
  • 3 Moreover, NLR was recently considered as part of the decision-making processes concerning the admission/recovery of patients with COVID-19 pneumonia.
Why It Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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