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Microbiota in health and diseases

📅 Published: April 23, 2022 👤 Kejun Hou, Zhuo‐Xun Wu, Xuan-Yu Chen et al. 📖 Signal Transduction and Targeted Therapy 📊 2,939 citations
AI-Generated Summary

The role of microbiota in health and diseases is being highlighted by numerous studies since its discovery. Then, we highlight the pathogenesis of microbiota dysbiosis in disease development and progression, primarily associated with dysregulation of community composition, modulation of host immune response, and induction of chronic inflammation.

⚡ This is an original paraphrased summary — not copied from the abstract. Full paper available at the source link below.

Key Findings
  • 1 Depending on the localized regions, microbiota can be classified into gut, oral, respiratory, and skin microbiota.
  • 2 The microbial communities are in symbiosis with the host, contributing to homeostasis and regulating immune function.
  • 3 However, microbiota dysbiosis can lead to dysregulation of bodily functions and diseases including cardiovascular diseases (CVDs), cancers, respiratory diseases, etc.
Why It Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

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