Challenges in the application of NGS in the clinical laboratory.

Next-generation sequencing (NGS), also known as massively parallel sequencing, has revolutionized genomic research. Challenges of NGS implementation in the clinical laboratory are also discussed, including sequencing error rate, bioinformatics, result interpretation, analytic sensitivity, as well as large data storage.

⚡ This is an original paraphrased summary — not copied from the abstract. Full paper available at the source link below.

• 1 The current advances in NGS technology make it possible to provide high resolution, high throughput HLA typing in clinical laboratories.
• 2 The focus of this review is on the recent development and implementation of NGS in clinical laboratories.
• 3 Here, we examine the critical role of NGS technologies in clinical immunology for HLA genotyping.

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

This summary is based on publicly available metadata and abstract. For the full research paper, visit the original source: