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An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases

📅 Published: May 25, 2022 👤 Daniel Mihai Teleanu, Adelina-Gabriela Niculescu, Iulia Ioana Lungu et al. 📖 International Journal of Molecular Sciences 📊 966 citations
AI-Generated Summary

Oxidative stress has been linked with a variety of diseases, being involved in the debut and/or progress of several neurodegenerative disorders. Nonetheless, there are still several mechanisms that need to be understood regarding the onset and the progress of neurodegenerative diseases in order to develop efficient therapies.

⚡ This is an original paraphrased summary — not copied from the abstract. Full paper available at the source link below.

Key Findings
  • 1 This review intends to summarize some of the findings that correlate the overproduction of reactive oxygen species with the pathophysiology of Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis.
  • 2 Oxidative stress was also noted to modify the inflammatory response.
  • 3 Even though oxidative stress and neuroinflammation are two totally different pathological events, they are linked and affect one another.
Why It Matters

Understanding this could lead to better treatments, improved diagnostics, or a deeper grasp of how the human body works — benefiting patient care globally.

This summary is based on publicly available metadata and abstract. For the full research paper, visit the original source:

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Article Details
Source OpenAlex
Category 🧬 Medicine & Biology
Published May 25, 2022
Journal International Journal of Molecular Sciences
DOI 10.3390/ijms23115938
Citations 966
Authors Daniel Mihai Teleanu, Adelina-Gabriela Niculescu, Iulia Ioana Lungu, Crina Ioana Radu, Oana Aurelia Vladâcenco